About the position 

A 3-year postdoctoral fellow position is available at the Research Institute of Internal Medicine and the Norwegian PSC Research Center (NoPSC) at Oslo University Hospital. The project is funded by the Research Council of Norway FRIPRO project 4DINFLAMMABILE.

NoPSC is dedicated to research on the chronic liver disease known as primary sclerosing cholangitis (PSC). The NoPSC center comprises three research groups covering all aspects of research related to primary sclerosing cholangitis, from basic genomic and experimental studies to clinical research and clinical trials. The research environment is world-leading for PSC and includes 30-35 engaged researchers from several countries and specialties.

The immune system plays a clear role in the pathogenesis of PSC, but the specific inflammatory mechanisms leading to the destruction of the bile ducts remain unknown. 

We invite highly motivated candidates with an interest in liver disease, immunology, and multiomic methodologies (sequencing-based and protein phenotyping) to apply for the postdoctoral position.

Project description

The postdoc will participate in the ongoing 4DINFLAMMABILE project, which aims to characterize bile duct inflammation in order to identify targetable molecular pathways using a range of multiomic techniques. In-depth characterization of animal models of bile duct inflammation and patients with PSC has been performed using spatial transcriptomics and single-cell sequencing (10x Genomics), mainly focusing on liver tissue.

Responsibilities

Our new colleague will take on the challenging task of extending transcriptomic findings to the protein level using various state-of-the-art staining techniques, such as tissue CyTOF, CLARITY, and single-cell/spatial proteomics. A key task will also be to integrate sequencing-based datasets with proteomics, in collaboration with our bioinformaticians.

The duration of appointment is 3 years.

Qualifications 

Required selection criteria 

• A degree equivalent to a Norwegian doctoral degree in molecular biology or immunology. The doctoral dissertation must be submitted for evaluation by the closing date. Appointment is dependent on the approval of the public defense of the doctoral thesis.
• The ability to design, plan, and interpret original experiments in an independent and innovative way.
• Experience with sequencing-based methods for immunological characterization.
• Fluent oral and written communication skills in English.

 Preferred selection criteria

• A strong background in imaging techniques and proteomics.
• Fluent oral and written communication skills in a Scandinavian language.

Personal qualities

• Well organized with high working capacity and productivity.
• Excellent team working skills.
• Strong motivation for a career in science, including project management and scientific writing.

Employment in the position is based on a comprehensive assessment of all qualification requirements applicable to the position, including personal qualifications.

We offer / We can offer you / Why should you choose us?

• Exciting and meaningful tasks in an organization with an important societal mission, contributing to knowledge development, education, and enlightenment that promote sustainable, fair, and knowledge-based societal development.
• Committed colleagues in a good working environment. 
• Good welfare schemes.
• Opportunity of up to 1.5 hours a week of exercise during working hours.
• A workplace with good development and career opportunities. 
• Membership in the Statens Pensjonskasse, which is one of Norway's best pension schemes with beneficial mortgages and good insurance schemes.
• Salary in position as Postdoctoral Fellow, position code 1352 in salary range NOK from 595 000 – 658 000, depending on competence and experience. Higher salary can be offered to particularly qualified candidates. From the salary, 2 percent is deducted in statutory contributions to the State Pension Fund.

Read more about the benefits of working in the public sector at Employer Portal.

Inclusive worklife and diversity at UiO

Inclusion and diversity are a strength. The University of Oslo has a personnel policy objective of achieving a balanced gender composition. Furthermore, we want employees with diverse professional expertise, life experience and perspectives.

If there are qualified applicants with disabilities, employment gaps or immigrant background, we will invite at least one applicant from each of these categories to an interview.

We hope that you will apply for the position. 

More information about gender equality initiatives at UiO can be found here.

Application

Your application should include:

• Application letter.
• CV.
• A complete list of publications.
• Transcripts and certificates.
• Contact information for 2-3 references.

Application with attachments must be submitted via our recruitment system Jobbnorge, click "Apply for the position".

When applying for the position, we ask you to retrieve your education results from Vitnemålsportalen.no. If your education results are not available through Vitnemålsportalen, we ask you to upload copies of your transcripts or grades. Please note that all documentation must be in English or a Scandinavian language.

General information

The best qualified candidates will invited for interviews. 

Applicant lists can be published in accordance with Norwegian Freedom of Information Act § 25. When you apply for a position with us, your name will appear on the public applicant list. It is possible to request to be excluded from this list. You must justify why you want an exemption from publication and we will then decide whether we can grant your request. If we can't, you will hear from us.

Please refer to Regulations for the Act on universities and colleges chapter 3 (Norwegian) and Guidelines concerning appointment to post doctoral and research posts at UiO (Norwegian).

The University of Oslo has a transfer agreement with all employees that is intended to secure the rights to all research results etc.